KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HEATR1
All Species:
26.36
Human Site:
T2042
Identified Species:
44.62
UniProt:
Q9H583
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H583
NP_060542.4
2144
242370
T2042
E
K
F
Q
E
R
V
T
K
H
L
I
P
C
I
Chimpanzee
Pan troglodytes
XP_001156974
2144
242420
T2042
E
K
F
Q
E
R
V
T
K
H
L
I
P
C
I
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536334
2141
242568
T2039
A
H
F
Q
E
R
V
T
K
H
L
I
P
C
I
Cat
Felis silvestris
Mouse
Mus musculus
NP_659084
2143
242053
T2041
E
R
F
Q
E
R
V
T
K
Y
L
V
P
C
I
Rat
Rattus norvegicus
NP_001101888
2143
241191
T2041
D
R
F
Q
E
R
V
T
K
H
L
V
P
C
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422958
2155
244590
T2053
E
K
F
Q
E
R
V
T
A
H
L
V
P
C
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7SY48
2159
242032
T2057
E
T
Y
K
S
R
I
T
T
H
L
V
P
C
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VM75
2096
237201
L1994
L
V
L
G
N
E
S
L
Q
Q
V
L
S
N
C
Honey Bee
Apis mellifera
XP_393800
2028
231830
K1926
E
D
Y
Q
K
R
A
K
E
L
I
V
P
C
I
Nematode Worm
Caenorhab. elegans
Q23495
1650
185210
R1556
H
L
V
P
A
I
Y
R
I
G
N
A
D
P
D
Sea Urchin
Strong. purpuratus
XP_794611
1635
181917
E1541
Q
D
L
I
F
D
Q
E
S
H
S
P
R
Q
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C8Z4
2001
224001
D1899
V
P
S
V
D
E
V
D
D
L
L
V
S
C
I
Baker's Yeast
Sacchar. cerevisiae
P42945
1769
200063
S1675
K
A
I
G
A
L
A
S
N
N
S
G
V
D
E
Red Bread Mold
Neurospora crassa
Q7RZM8
1788
196873
E1694
D
L
V
L
A
V
V
E
L
A
A
A
A
D
S
Conservation
Percent
Protein Identity:
100
99.5
N.A.
89.7
N.A.
83.8
84.9
N.A.
N.A.
65.5
N.A.
54.5
N.A.
28.6
30.5
21.1
24.4
Protein Similarity:
100
99.8
N.A.
95
N.A.
92.1
92.7
N.A.
N.A.
80.5
N.A.
73
N.A.
49.4
50.8
38.9
43.2
P-Site Identity:
100
100
N.A.
86.6
N.A.
80
80
N.A.
N.A.
86.6
N.A.
53.3
N.A.
0
40
0
6.6
P-Site Similarity:
100
100
N.A.
86.6
N.A.
100
100
N.A.
N.A.
93.3
N.A.
80
N.A.
20
73.3
0
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.4
21.2
23
Protein Similarity:
N.A.
N.A.
N.A.
43.4
40.2
42.2
P-Site Identity:
N.A.
N.A.
N.A.
26.6
0
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
40
20
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
22
0
15
0
8
8
8
15
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
65
8
% C
% Asp:
15
15
0
0
8
8
0
8
8
0
0
0
8
15
8
% D
% Glu:
43
0
0
0
43
15
0
15
8
0
0
0
0
0
8
% E
% Phe:
0
0
43
0
8
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
15
0
0
0
0
0
8
0
8
0
0
0
% G
% His:
8
8
0
0
0
0
0
0
0
50
0
0
0
0
0
% H
% Ile:
0
0
8
8
0
8
8
0
8
0
8
22
0
0
65
% I
% Lys:
8
22
0
8
8
0
0
8
36
0
0
0
0
0
0
% K
% Leu:
8
15
15
8
0
8
0
8
8
15
58
8
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
0
8
8
8
0
0
8
0
% N
% Pro:
0
8
0
8
0
0
0
0
0
0
0
8
58
8
0
% P
% Gln:
8
0
0
50
0
0
8
0
8
8
0
0
0
8
0
% Q
% Arg:
0
15
0
0
0
58
0
8
0
0
0
0
8
0
0
% R
% Ser:
0
0
8
0
8
0
8
8
8
0
15
0
15
0
8
% S
% Thr:
0
8
0
0
0
0
0
50
8
0
0
0
0
0
0
% T
% Val:
8
8
15
8
0
8
58
0
0
0
8
43
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
15
0
0
0
8
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _